| Year |
Title |
Role |
Notes |
| 1987 |
Firehouse |
Babs |
|
| 1988 |
Blood Red |
Maria Collogero |
|
| Miami Vice |
Polly Wheeler |
TV (season 4 episode 22: Mirror Image) |
| Mystic Pizza |
Daisy Arujo |
Independent Spirit Award Nomination: Best Lead Actress |
| Baja Oklahoma |
Candy Hutchins |
TV |
| Satisfaction |
Daryle |
Also known as Girls of Summer |
| 1989 |
Steel Magnolias |
Shelby Eatenton Latcherie |
Academy Award nomination: Best Supporting Actress
Golden Globe win: Best Supporting Actress |
| 1990 |
Flatliners |
Rachel Mannus |
|
| Pretty Woman |
Vivian Ward |
Academy Award nomination: Best Actress
BAFTA nomination: Best Actress
Golden Globe win: Best Musical/Comedy Actress |
| 1991 |
Hook |
Tinkerbell |
Razzie Award Worst Supporting Actress |
| Dying Young |
Hilary O’Neil |
|
| Sleeping with the Enemy |
Sara Waters/Laura Burney |
|
| 1992 |
The Player |
|
Cameo |
| 1993 |
The Pelican Brief |
Darby Shaw |
|
| 1994 |
Prêt-à-Porter |
Anne Eisenhower |
Also known as Ready to Wear |
| I Love Trouble |
Sabrina Peterson |
|
| 1995 |
Something to Talk About |
Grace King Bichon |
|
| 1996 |
Everyone Says I Love You |
Von Sidell |
|
| Michael Collins |
Kitty Kiernan |
|
| Mary Reilly |
Mary Reilly |
Razzie Award Worst Actress |
| 1997 |
Conspiracy Theory |
Alice Sutton |
|
| My Best Friend’s Wedding |
Julianne Potter |
Golden Globe nomination: Best Musical/Comedy Actress |
| 1998 |
Stepmom |
Isabel Kelly |
|
| 1999 |
Runaway Bride |
Maggie Carpenter |
|
| Notting Hill |
Anna Scott |
Golden Globe nomination: Best Musical/Comedy Actress |
| 2000 |
Erin Brockovich |
Erin Brockovich |
Academy Award win: Best Actress
BAFTA win: Best Actress
Golden Globe win: Best Drama Actress |
| 2001 |
Ocean’s Eleven |
Tess Ocean |
|
| America’s Sweethearts |
Kathleen “Kiki” Harrison |
|
| The Mexican |
Samantha Barzel |
|
| 2002 |
Confessions of a Dangerous Mind |
Patricia Watson |
|
| Grand Champion |
Jolene |
|
| Full Frontal |
Catherine/Francesca |
|
| 2003 |
Mona Lisa Smile |
Katherine Ann Watson |
|
| 2004 |
Ocean’s Twelve |
Tess Ocean |
|
| Closer |
Anna Cameron |
|
| 2006 |
Charlotte’s Web |
Charlotte the Spider (voice) |
|
| Beslan: Three Days In September |
Narrator |
| The Ant Bully |
Hova (voice) |
|
| 2007 |
Charlie Wilson’s War |
Joanne Herring |
Golden Globe nomination – Best Supporting Actress |
| 2008 |
Fireflies in the Garden |
Lisa Waechter |
|
| 2009 |
Duplicity |
Claire Stenwick |
|
| 2010 |
The Friday Night Knitting Club |
Georgia Walker |
forthcoming film |
Duplicity 
Valentine's Day
Eat, Pray, Love
